Title : GABA-labeled terminals form proportionally more synapses with dopaminergic neurons containing low densities of tyrosine hydroxylase-immunoreactivity in rat ventral tegmental area.

Pub. Date : 1991 Sep 13

PMID : 1685938






6 Functional Relationships(s)
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1 GABA-labeled terminals form proportionally more synapses with dopaminergic neurons containing low densities of tyrosine hydroxylase-immunoreactivity in rat ventral tegmental area. gamma-Aminobutyric Acid tyrosine hydroxylase Rattus norvegicus
2 With both methods, most GABA-labeled terminals (63% for SIG, 66% for PAP) formed direct synapses with TH-labeled profiles. gamma-Aminobutyric Acid tyrosine hydroxylase Rattus norvegicus
3 In single sections where GABA-labeled terminals were presynaptic to TH-labeled profiles, they comprised 45% (PAP) to 54% (SIG) of the total number of synaptic inputs onto TH-labeled cell bodies and 65% (SIG) to 80% (PAP) of the synaptic input onto TH-labeled dendrites. gamma-Aminobutyric Acid tyrosine hydroxylase Rattus norvegicus
4 In single sections where GABA-labeled terminals were presynaptic to TH-labeled profiles, they comprised 45% (PAP) to 54% (SIG) of the total number of synaptic inputs onto TH-labeled cell bodies and 65% (SIG) to 80% (PAP) of the synaptic input onto TH-labeled dendrites. gamma-Aminobutyric Acid tyrosine hydroxylase Rattus norvegicus
5 In single sections where GABA-labeled terminals were presynaptic to TH-labeled profiles, they comprised 45% (PAP) to 54% (SIG) of the total number of synaptic inputs onto TH-labeled cell bodies and 65% (SIG) to 80% (PAP) of the synaptic input onto TH-labeled dendrites. gamma-Aminobutyric Acid tyrosine hydroxylase Rattus norvegicus
6 However, lightly TH-labeled neurons received fewer synaptic contacts from unlabeled terminals and, consequently, received proportionally more GABA-labeled terminals. gamma-Aminobutyric Acid tyrosine hydroxylase Rattus norvegicus