Pub. Date : 2006 Dec
PMID : 16856883
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The effects of human CYP2C8 genotype and fluvoxamine on the pharmacokinetics of rosiglitazone in healthy subjects. | Rosiglitazone | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |
2 | AIMS: To determine the effect of CYP2C8 genotype and of fluvoxamine on the pharmacokinetics of rosiglitazone. | Rosiglitazone | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |
3 | CONCLUSION: The importance of the CYP2C8*3 mutation in the in vivo metabolism of rosiglitazone could not be confirmed. | Rosiglitazone | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |