Title : The cytoplasmic domain of Fas ligand costimulates TCR signals.

Pub. Date : 2006 Aug 1

PMID : 16849454






1 Functional Relationships(s)
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1 We further show that the proline-rich intracellular domain of FasL is sufficient to costimulate by enhancing the phosphorylation of Akt, ERK1/2, JNK, and FasL itself, by activating the transcription factors NFAT and AP-1, and by enhancing IFN-gamma production. Proline AKT serine/threonine kinase 1 Homo sapiens