Title : Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ.

Pub. Date : 2006 Oct 15

PMID : 16848763






1 Functional Relationships(s)
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1 Further experiments showed that DAZAP1 was phosphorylated stoichiometrically in vitro by ERK2 (extracellular-signal-regulated protein kinase 2) at two Thr-Pro sequences (Thr269 and Thr315), and that both sites became phosphorylated in HEK-293 (human embryonic kidney 293) cells in response to PMA or EGF (epidermal growth factor), or RAW 264.7 macrophages in response to LPS. Proline mitogen-activated protein kinase 1 Homo sapiens