Title : Matrix metalloproteinase-7 and epidermal growth factor receptor mediate hypoxia-induced extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase activation and subsequent proliferation in bladder smooth muscle cells.

Pub. Date : 2006 May-Jun

PMID : 16848631






1 Functional Relationships(s)
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1 We conclude that hypoxia leads to Erk1/2 activation, which appears to modulate BSMC proliferation through MMP-7-and EGFR-mediated mechanisms. bsmc epidermal growth factor receptor Rattus norvegicus