Pub. Date : 2006 Aug 7
PMID : 16847070
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Consistent with a role for oxidative stress in this effect, in vitro H2O2 treatment of RAW 264.7 macrophages similarly caused an increase in surface TLR4. | Hydrogen Peroxide | toll like receptor 4 | Homo sapiens |
| 2 | The H2O2-induced increase in surface TLR4 was prevented by depleting intracellular calcium or disrupting the cytoskeleton, suggesting the involvement of receptor exocytosis. | Hydrogen Peroxide | toll like receptor 4 | Homo sapiens |
| 3 | Preventing the oxidant-induced movement of TLR4 to lipid rafts using methyl-beta-cyclodextrin precluded the increased responsiveness of cells to LPS after H2O2 treatment. | Hydrogen Peroxide | toll like receptor 4 | Homo sapiens |