Title : Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells.

Pub. Date : 2006 Jul

PMID : 16841962






2 Functional Relationships(s)
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1 Myeloperoxidase-catalyzed metabolism of etoposide to its quinone and glutathione adduct forms in HL60 cells. Glutathione myeloperoxidase Homo sapiens
2 More importantly, the formation of the glutathione adduct was significantly suppressed by the pretreatment of HL60 cells with the heme synthesis inhibitor succinylacetone (p < 0.001), which resulted in a decreased level and activity of MPO. Glutathione myeloperoxidase Homo sapiens