Title : Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine.

Pub. Date : 2006 Oct

PMID : 16837570






2 Functional Relationships(s)
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1 The hydrolytic activity of hCE-2 increased with increasing alcohol chain length in benzoic acid derivative substrates, whereas hCE-1 preferentially catalyzed the hydrolysis of substrates with short alcohol chains. Alcohols carboxylesterase 1 Homo sapiens
2 Furthermore, the addition of hydrophobic alcohols to the reaction mixture with p-aminobenzoic acid propyl ester induced high and low levels of transesterification by hCE-1 and hCE-2, respectively. Alcohols carboxylesterase 1 Homo sapiens