Pub. Date : 2006 Dec
PMID : 16835400
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The PPARgamma agonist pioglitazone modifies the vascular sodium-angiotensin II relationship in insulin-resistant rats. | Pioglitazone | angiotensinogen | Rattus norvegicus |
| 2 | Pioglitazone blunted the systemic response to ANG II and abolished the increased responsiveness to ANG II induced by a HS diet. | Pioglitazone | angiotensinogen | Rattus norvegicus |
| 3 | Pioglitazone blunted the systemic response to ANG II and abolished the increased responsiveness to ANG II induced by a HS diet. | Pioglitazone | angiotensinogen | Rattus norvegicus |
| 4 | Pioglitazone modified the renal hemodynamic response to changes in salt intake while maintaining a lower filtration fraction with ANG II perfusion. | Pioglitazone | angiotensinogen | Rattus norvegicus |
| 5 | In conclusion, these data demonstrate that the peroxisome proliferator-activated receptor-gamma agonist pioglitazone modifies the physiological relationship between sodium chloride and the response to ANG II in insulin-resistant rats. | Pioglitazone | angiotensinogen | Rattus norvegicus |