Title : Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function.

Pub. Date : 2006 Sep

PMID : 16835316






3 Functional Relationships(s)
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1 In the present study, we show that human peripheral blood monocytes express a DP IV-like enzyme activity, which could be inhibited completely by the synthetic DP IV inhibitor Lys[Z(NO(2))]-thiazolidide. lysyl-(Z(nitro))thiazolidide dipeptidyl peptidase 4 Homo sapiens
2 In the present study, we show that human peripheral blood monocytes express a DP IV-like enzyme activity, which could be inhibited completely by the synthetic DP IV inhibitor Lys[Z(NO(2))]-thiazolidide. lysyl-(Z(nitro))thiazolidide dipeptidyl peptidase 4 Homo sapiens
3 Inhibitor kinetic studies with purified human plasma attractin revealed that Lys[Z(NO(2))]-thiazolidide not only inhibits DP IV but also attractin (50% inhibition concentration=8.45 x 10(-9) M). lysyl-(Z(nitro))thiazolidide dipeptidyl peptidase 4 Homo sapiens