Title : Acute capsaicin injection increases nicotinamide adenine dinucleotide phosphate diaphorase staining independent of Fos activation in the rat dorsolateral periaqueductal gray.

Pub. Date : 2006 Sep 1

PMID : 16835009






3 Functional Relationships(s)
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1 The aim of this study was to determine how the noxious stimulant capsaicin affects intracellular dynamics in the dlPAG evidenced by Fos protein immunoreactivity (index of intracellular activation) and the NADPH-d reactivity. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 Compared to vehicle, capsaicin (50mg/kg, subcutaneous) significantly increased NADPH-d reactivity and Fos expression along the dlPAG neuraxis. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
3 However, less than one percent of the capsaicin-induced Fos activation occurred in NADPH-d-positive cells. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus