Title : Coupling mitochondrial respiratory chain to cell death: an essential role of mitochondrial complex I in the interferon-beta and retinoic acid-induced cancer cell death.

Pub. Date : 2007 Feb

PMID : 16826196






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mitochondrial-nuclear translocation of these subunits was not observed, but overproduction of reactive oxygen species (ROS), which causes loss of mitochondrial function, was detected upon IFN-beta/RA treatment. Reactive Oxygen Species interferon beta 1 Homo sapiens
2 Mitochondrial-nuclear translocation of these subunits was not observed, but overproduction of reactive oxygen species (ROS), which causes loss of mitochondrial function, was detected upon IFN-beta/RA treatment. Reactive Oxygen Species interferon beta 1 Homo sapiens
3 Our data suggest that the MRC regulates IFN-beta/RA-induced cell death by modulating ROS production and late gene expression. Reactive Oxygen Species interferon beta 1 Homo sapiens