Title : P-glycoprotein expression and DNA topoisomerase I and II activity in benign tumors of the ovary and in malignant tumors of the ovary, before and after platinum/cyclophosphamide chemotherapy.

Pub. Date : 1991 Nov 1

PMID : 1682037






1 Functional Relationships(s)
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1 P-gp expression (range, 5-100% positive staining cells) was found in 3 of 6 cystadenomas, 0 of 2 borderline tumors, 15 of 21 untreated ovarian cancers, and 8 of 13 platinum/cyclophosphamide treated ovarian cancers. Cyclophosphamide ATP binding cassette subfamily B member 1 Homo sapiens