Title : Secretagogue-specific effects of interleukin-1 on gastric acid secretion.

Pub. Date : 1991 Oct

PMID : 1681735






2 Functional Relationships(s)
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1 In the present study, the effects of IL-1 beta on pentagastrin-stimulated acid secretion were compared with those of two other cytokines, namely IL-1 alpha and tumor necrosis factor (TNF) alpha. Pentagastrin interleukin 1 beta Rattus norvegicus
2 These results demonstrate that IL-1 beta is an extremely potent inhibitor of acid secretion stimulated by pentagastrin but not that stimulated by histamine or bethanechol, through a mechanism that is at least in part independent of the vagus nerve and of prostaglandin synthesis. Pentagastrin interleukin 1 beta Rattus norvegicus