Pub. Date : 2006 Oct 15
PMID : 16803457
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Quenching of intrinsic Pgp tryptophan fluorescence by acrylamide, iodide and caesium indicated that conformational changes took place upon formation of the trapped complexes. | Acrylamide | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Trapping with V(i) and ATP led to a 6-fold increase in the acrylamide quenching constant, K(SV), suggesting that large conformational changes take place in the Pgp transmembrane regions on trapping in the forward direction. | Acrylamide | ATP binding cassette subfamily B member 1 | Homo sapiens |