Pub. Date : 1999
PMID : 16801118
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In Bromadryl-treated platelets, a very good correlation was found between aggregation and liberation of arachidonic acid; the correlation coefficients calculated for thrombin- and A23187-stimulated platelets were 0.94123 and 0.98611, respectively. | Arachidonic Acid | coagulation factor II, thrombin | Homo sapiens |
| 2 | However, in platelets stimulated with thrombin, thromboxane formation was decreased at a lower mean inhibitory concentration of Bromadryl (6 micromol/litre) than arachidonic acid liberation (72 micromol/litre); thus, phospholipase A(2) does not seem to be the only site in the arachidonate metabolism cascade affected by Bromadryl. | Arachidonic Acid | coagulation factor II, thrombin | Homo sapiens |
| 3 | However, in platelets stimulated with thrombin, thromboxane formation was decreased at a lower mean inhibitory concentration of Bromadryl (6 micromol/litre) than arachidonic acid liberation (72 micromol/litre); thus, phospholipase A(2) does not seem to be the only site in the arachidonate metabolism cascade affected by Bromadryl. | Arachidonic Acid | coagulation factor II, thrombin | Homo sapiens |