Pub. Date : 2006 Jul
PMID : 16799975
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The constitutive androstane receptor (CAR; NR1I3) and to a lesser extent the pregnane X receptor (PXR; NR1I2) are responsible for mediating induction of many phenobarbital-responsive genes. | Phenobarbital | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 2 | The constitutive androstane receptor (CAR; NR1I3) and to a lesser extent the pregnane X receptor (PXR; NR1I2) are responsible for mediating induction of many phenobarbital-responsive genes. | Phenobarbital | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 3 | The constitutive androstane receptor (CAR; NR1I3) and to a lesser extent the pregnane X receptor (PXR; NR1I2) are responsible for mediating induction of many phenobarbital-responsive genes. | Phenobarbital | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |
| 4 | In addition, nuclear expression of HNF-4alpha protein is significantly elevated 3 hours after the administration of phenobarbital in wild-type, CAR-/-, and CAR-/-/PXR-/- mice. | Phenobarbital | nuclear receptor subfamily 1, group I, member 2 | Mus musculus |