Title : Quantitative structure-activity relationships (QSars) in CYP3A4 inhibitors: the importance of lipophilic character and hydrogen bonding.

Pub. Date : 2006 Apr

PMID : 16789425






1 Functional Relationships(s)
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1 This is evidenced by linear correlations between inhibition of CYP3A4 and the octanol-water partition coefficient (P value) when expressed logarithmically (ie., log P). Octanols cytochrome P450 family 3 subfamily A member 4 Homo sapiens