Title : Effects of leukotriene receptor antagonists on monocyte chemotaxis, p38 and cytoplasmic calcium.

Pub. Date : 2006 Jun

PMID : 16771778






2 Functional Relationships(s)
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1 Montelukast also abolished MCP-1-induced [Ca2+]i and pp38 MAPK expression in THP-1 cells in a dose-dependent manner. montelukast C-C motif chemokine ligand 2 Homo sapiens
2 These data demonstrate that montelukast is effective in down-regulating human monocyte chemotaxis induced by MCP-1. montelukast C-C motif chemokine ligand 2 Homo sapiens