Title : The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum.

Pub. Date : 2006 Sep

PMID : 16759735






4 Functional Relationships(s)
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1 The bipolar disorder treatment, valproic acid (VPA), increases the activity of this pathway by modulating extracellular signal-regulated kinase 2 (ERK2) phosphorylation through an unknown mechanism. Valproic Acid mitogen-activated protein kinase 1 Homo sapiens
2 The bipolar disorder treatment, valproic acid (VPA), increases the activity of this pathway by modulating extracellular signal-regulated kinase 2 (ERK2) phosphorylation through an unknown mechanism. Valproic Acid mitogen-activated protein kinase 1 Homo sapiens
3 We find that, similar to mammalian systems, VPA causes a transient increase in the activation of the MAPK signalling pathway, as shown by ERK2 phosphorylation. Valproic Acid mitogen-activated protein kinase 1 Homo sapiens
4 We find that, similar to mammalian systems, VPA causes a transient increase in the activation of the MAPK signalling pathway, as shown by ERK2 phosphorylation. Valproic Acid mitogen-activated protein kinase 1 Homo sapiens