Title : Fibroblast growth factor-2 is an immediate-early gene induced by mechanical stress in osteogenic cells.

Pub. Date : 2006 Jun

PMID : 16753025






2 Functional Relationships(s)
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1 Pretreating MC3T3-E1 cells with the mitogen-activated protein kinase (MAPK)/ERK kinase 1/2 (MEK1/2) inhibitor, U0126, or H-89, a PKA inhibitor, significantly inhibited the induction of fgf-2, showing that mechanical induction of fgf-2 is dependent on ERK and PKA signaling pathways. U 0126 fibroblast growth factor 2 Mus musculus
2 Pretreating MC3T3-E1 cells with the mitogen-activated protein kinase (MAPK)/ERK kinase 1/2 (MEK1/2) inhibitor, U0126, or H-89, a PKA inhibitor, significantly inhibited the induction of fgf-2, showing that mechanical induction of fgf-2 is dependent on ERK and PKA signaling pathways. U 0126 fibroblast growth factor 2 Mus musculus