Title : Gingerol metabolite and a synthetic analogue Capsarol inhibit macrophage NF-kappaB-mediated iNOS gene expression and enzyme activity.

Pub. Date : 2006 Jun

PMID : 16732525






1 Functional Relationships(s)
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1 This occurred at the transcriptional level, since the gingerol compounds decreased LPS-induced IkappaB-alpha degradation, prevented nuclear translocation of NF-kappaB p65 and reduced NF-kappaB activity in a concentration-dependent manner. gingerol nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus