Title : Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma.

Pub. Date : 2006 Jul

PMID : 16723633






1 Functional Relationships(s)
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1 Interestingly, the BBR compounds and cisplatin both induced extracellular signal-regulated kinase 1/2 phosphorylation, and inhibition of this pathway at the level of MEK antagonized the induction of G2/M arrest or apoptosis, respectively. Cisplatin mitogen-activated protein kinase 3 Homo sapiens