Pub. Date : 2006 Aug 15
PMID : 16712891
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, atRA treatment caused a strong and sustained activation of c-Jun N-terminal kinase (JNK) and p38 kinase (p38), as well as an early but transient activation of extracellular signal-regulated kinase (ERK). | Tretinoin | mitogen-activated protein kinase 14 | Mus musculus |
| 2 | In addition, atRA treatment caused a strong and sustained activation of c-Jun N-terminal kinase (JNK) and p38 kinase (p38), as well as an early but transient activation of extracellular signal-regulated kinase (ERK). | Tretinoin | mitogen-activated protein kinase 14 | Mus musculus |
| 3 | Importantly, atRA-induced DNA fragmentation and capase-3 activation were prevented by pretreatment with the JNK inhibitor (SP600125) and the p38 MAPK inhibitor (SB202190), but not by pretreatment with MEK inhibitor (U0126). | Tretinoin | mitogen-activated protein kinase 14 | Mus musculus |