Title : Measurement of carnitine biosynthesis enzyme activities by tandem mass spectrometry: differences between the mouse and the rat.

Pub. Date : 2006 Jul 1

PMID : 16707092






1 Functional Relationships(s)
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1 We developed two simple tandem mass spectrometry-based methods to determine the activity of three carnitine biosynthesis enzymes (6-N-trimethyllysine dioxygenase, 4-trimethylaminobutyraldehyde dehydrogenase, and 4-trimethylaminobutyric acid dioxygenase) in total homogenates that can be prepared from frozen tissue. Carnitine aldehyde dehydrogenase 9, subfamily A1 Mus musculus