Title : Somatic VHL gene alterations in MEN2-associated medullary thyroid carcinoma.

Pub. Date : 2006 May 17

PMID : 16707008






1 Functional Relationships(s)
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1 CONCLUSION: These data suggest that a RET germline mutation is necessary for development of CCH, that allelic imbalance between mutant and wild-type RET may set off tumorigenesis, and that somatic VHL gene alterations may not play a major role in tumorigenesis of MEN2A-associated MTC. 1-acetyl-2-(coumariniminecarboxamide-3-yl)hydrazine ret proto-oncogene Homo sapiens