Title : Glutamine pretreatment reduces IL-8 production in human intestinal epithelial cells by limiting IkappaBalpha ubiquitination.

Pub. Date : 2006 Jun

PMID : 16702304






3 Functional Relationships(s)
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1 Glutamine pretreatment reduces IL-8 production in human intestinal epithelial cells by limiting IkappaBalpha ubiquitination. Glutamine C-X-C motif chemokine ligand 8 Homo sapiens
2 Because regulation of the inflammatory response was shown to be linked to proteolysis regulation, we hypothesized that glutamine pretreatment could act on IL-8 production in human intestinal epithelial cells through the regulation of inhibitor kappaB (IkappaB) ubiquitination. Glutamine C-X-C motif chemokine ligand 8 Homo sapiens
3 A pretreatment with 10 mmol/L glutamine decreased IL-8 production under both basal and proinflammatory conditions (both P < 0.05). Glutamine C-X-C motif chemokine ligand 8 Homo sapiens