Title : Cytoprotection by lithium and valproate varies between cell types and cellular stresses.

Pub. Date : 2006 Jun 6

PMID : 16678157






1 Functional Relationships(s)
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1 Pretreatment of SH-SY5Y cells for 7 days, but not 1 day, with 1 mM of lithium or 0.6 mM of valproate significantly reduced rotenone and H2O2-induced cytotoxicity, cytochrome c release and caspase-3 activation, and increased Bcl-2 levels. Valproic Acid caspase 3 Homo sapiens