Title : Bisphosphonates inhibit the growth of mesothelioma cells in vitro and in vivo.

Pub. Date : 2006 May 1

PMID : 16675582






3 Functional Relationships(s)
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1 Both bisphosphonates also induced the phosphorylation of the p38 mitogen-activated protein kinase in AB12 and AC29 cells. Diphosphonates mitogen-activated protein kinase 14 Mus musculus
2 The inhibition of p38 augmented bisphosphonate-induced growth inhibition in these cells. Diphosphonates mitogen-activated protein kinase 14 Mus musculus
3 Bisphosphonate-induced p38 phosphorylation was not reversible by geranylgeraniol. Diphosphonates mitogen-activated protein kinase 14 Mus musculus