Title : Developmental regulation of prostacyclin synthase and prostacyclin receptors in the ovine uterus and conceptus during the peri-implantation period.

Pub. Date : 2006 May

PMID : 16672356






2 Functional Relationships(s)
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1 The membrane receptor for PGI2 (PTGIR) and the nuclear receptors, i.e. peroxisome proliferator-activated receptors (PPAR) and their heterodimer partners the retinoid X receptors (RXR), were analysed. Epoprostenol prostaglandin I2 receptor Homo sapiens
2 Our results also underline the importance of PTGIS and PPARD in the trophoblast and PTGIR in the uterus, suggesting that PGI2 is of both uterine and trophoblastic origin and is involved in a complex signalling pathway at around the time of implantation in the ewe. Epoprostenol prostaglandin I2 receptor Homo sapiens