Title : Influence of staurosporine, nitrendipine and monooleoylglycerol on interleukin-1-induced insulin secretion and phosphoinositide hydrolysis.

Pub. Date : 1991 Dec

PMID : 1665456






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The monokine interleukin-1 alpha (IL-1) induces a glucose-dependent increase in insulin secretion, an effect tentatively attributed to its ability to increase beta cell phosphoinositide (PI) hydrolysis. Glucose interleukin 1 alpha Homo sapiens
2 The monokine interleukin-1 alpha (IL-1) induces a glucose-dependent increase in insulin secretion, an effect tentatively attributed to its ability to increase beta cell phosphoinositide (PI) hydrolysis. Glucose interleukin 1 alpha Homo sapiens
3 In perifused islets, insulin secretion in response to IL-1 in the presence of 7 mM glucose averaged 313 +/- 43 pg/islet/min 35-40 min after the onset of stimulation. Glucose interleukin 1 alpha Homo sapiens
4 This level of IL-1 caused significant increases in inositol phosphate accumulation in the presence of 7 mM glucose but not 2.75 mM glucose. Glucose interleukin 1 alpha Homo sapiens