Pub. Date : 2006 Oct 1
PMID : 16646054
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 2 | Dietary folate is associated with p16(INK4A) methylation in head and neck squamous cell carcinoma. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 3 | Decreased dietary folate in an animal model of hepatocellular carcinoma has been associated with the induction of epigenetic silencing of the p16(INK4A) gene. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 4 | Decreased dietary folate in an animal model of hepatocellular carcinoma has been associated with the induction of epigenetic silencing of the p16(INK4A) gene. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 5 | In an ongoing population-based study of HNSCC, we sought to extend this observation to human disease testing the hypothesis that p16(INK4A) methylation is associated with decreased dietary folate. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 6 | In an ongoing population-based study of HNSCC, we sought to extend this observation to human disease testing the hypothesis that p16(INK4A) methylation is associated with decreased dietary folate. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 7 | In 169 HNSCCs, the odds ratio for p16(INK4A) methylation among those with low dietary folate intake was 2.3 (95% CI = 1.1-4.8) when compared with those with high folate intake. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 8 | In 169 HNSCCs, the odds ratio for p16(INK4A) methylation among those with low dietary folate intake was 2.3 (95% CI = 1.1-4.8) when compared with those with high folate intake. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 9 | Furthermore, this increased risk for epigenetic silencing at p16(INK4A) was modified by the MTHFR alleles previously associated with diminished serum folate levels. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 10 | Furthermore, this increased risk for epigenetic silencing at p16(INK4A) was modified by the MTHFR alleles previously associated with diminished serum folate levels. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 11 | Hence, in HNSCC low dietary intake of folate is associated with p16(INK4A) methylation, and this relationship is modified by the MTHFR genotype. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |
| 12 | Hence, in HNSCC low dietary intake of folate is associated with p16(INK4A) methylation, and this relationship is modified by the MTHFR genotype. | Folic Acid | cyclin dependent kinase inhibitor 2A | Homo sapiens |