Title : Influence of 17beta-estradiol and insulin on type II collagen and protein synthesis of articular chondrocytes.

Pub. Date : 2006 Aug

PMID : 16631425






2 Functional Relationships(s)
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1 Whereas insulin raised the proline incorporation and the type II collagen synthesis significantly, physiological doses of estradiol did not show significant effects. Proline insulin Homo sapiens
2 The stimulating effect of insulin on the [(3)H]-proline incorporation or the type II collagen synthesis was significantly suppressed after preincubation of cells with 10(-11) to 10(-9) M estradiol resembling an unfavorable effect for articular cartilage. Proline insulin Homo sapiens