Title : Induction of interleukin-1 production by ligands binding to the scavenger receptor in human monocytes and the THP-1 cell line.

Pub. Date : 1991 Nov

PMID : 1663075






3 Functional Relationships(s)
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1 Scavenger receptor-mediated IL-1 production was inhibited by H7, a protein kinase C inhibitor, and enhanced by IBMX, an inhibitor of cyclic AMP degradation, suggesting a synergistic effect of protein kinase C and cyclic AMP-mediated signal transduction pathways in scavenger receptor-mediated IL-1 production. Cyclic AMP interleukin 1 alpha Homo sapiens
2 Scavenger receptor-mediated IL-1 production was inhibited by H7, a protein kinase C inhibitor, and enhanced by IBMX, an inhibitor of cyclic AMP degradation, suggesting a synergistic effect of protein kinase C and cyclic AMP-mediated signal transduction pathways in scavenger receptor-mediated IL-1 production. Cyclic AMP interleukin 1 alpha Homo sapiens
3 Scavenger receptor-mediated IL-1 production was inhibited by H7, a protein kinase C inhibitor, and enhanced by IBMX, an inhibitor of cyclic AMP degradation, suggesting a synergistic effect of protein kinase C and cyclic AMP-mediated signal transduction pathways in scavenger receptor-mediated IL-1 production. Cyclic AMP interleukin 1 alpha Homo sapiens