Title : Modulation of IgE-dependent COX-2 gene expression by reactive oxygen species in human neutrophils.

Pub. Date : 2006 Jul

PMID : 16624933






1 Functional Relationships(s)
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1 Evidence is also presented, using Fe(2)(+)/Cu(2)(+) ions, that hydroxyl radicals generated from hydrogen peroxide through Fenton reactions could constitute candidate modulators able to directly trigger anti-IgE-elicited COX-2 expression through MAPK and NF-kappaB pathways. ammonium ferrous sulfate mitochondrially encoded cytochrome c oxidase II Homo sapiens