Title : Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.

Pub. Date : 2006 Jun

PMID : 16624932






1 Functional Relationships(s)
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1 Here, we describe that the IFN-beta released upon stimulation with lipopolysaccharide (LPS) or polyinosinic:polycytidylic acid (poly I:C) is responsible for a rapid and sustained signal transducer and activator of transcription 1 and 2 activation and expression of IFN-stimulated genes, such as the transcription factor IFN regulatory factor 7 and the chemokine CXC chemokine ligand 10. Poly C interferon beta 1 Homo sapiens