Title : AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

Pub. Date : 2006 May 28

PMID : 16620785






2 Functional Relationships(s)
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1 These findings show that Akt dephosphorylation often occurs concomitantly with AMPK activation when cells are treated with phenformin or AICAR, indicating that these drugs do not only affect AMPK but also cause a coordinated inverse regulation of AMPK and Akt. acadesine AKT serine/threonine kinase 1 Homo sapiens
2 These findings show that Akt dephosphorylation often occurs concomitantly with AMPK activation when cells are treated with phenformin or AICAR, indicating that these drugs do not only affect AMPK but also cause a coordinated inverse regulation of AMPK and Akt. acadesine AKT serine/threonine kinase 1 Homo sapiens