Title : [Effects of oxidative DNA damage and genetic polymorphism of the glutathione peroxidase 1 (GPX1) and 8-oxoguanine glycosylase 1 (hOGG1) on lung cancer].

Pub. Date : 2006 Mar

PMID : 16615267






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Individuals carrying the Pro/Leu or Leu/Leu genotype of GPX1 were at a higher risk for lung cancer (adjusted OR = 2.29). Leucine glutathione peroxidase 1 Homo sapiens
2 Individuals carrying the Pro/Leu or Leu/Leu genotype of GPX1 were at a higher risk for lung cancer (adjusted OR = 2.29). Leucine glutathione peroxidase 1 Homo sapiens
3 Individuals carrying the Pro/Leu or Leu/Leu genotype of GPX1 were at a higher risk for lung cancer (adjusted OR = 2.29). Leucine glutathione peroxidase 1 Homo sapiens
4 CONCLUSIONS: These results lead to a conclusion that individuals with the GPX1 Pro/Leu or Leu/Leu genotype would be more susceptible to the lung cancer induced by oxidative stress than those individuals with the Pro/Pro genotype. Leucine glutathione peroxidase 1 Homo sapiens