Pub. Date : 1991 Aug 19
PMID : 1661214
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Opposite effects of phospholipase A2 on [3H]AMPA binding in adult and neonatal membranes. | Tritium | phospholipase A2 group IB | Rattus norvegicus |
2 | In the present study, we compared the effect of phospholipase A2 (PLA2) treatment of synaptic membranes from adult and neonatal rats on the characteristics of [3H]AMPA binding sites. | Tritium | phospholipase A2 group IB | Rattus norvegicus |
3 | In the present study, we compared the effect of phospholipase A2 (PLA2) treatment of synaptic membranes from adult and neonatal rats on the characteristics of [3H]AMPA binding sites. | Tritium | phospholipase A2 group IB | Rattus norvegicus |
4 | Whereas PLA2 treatment of membranes from adult rats produces an increased affinity for [3H]AMPA binding, the same treatment in neonatal rats results in a decrease in the maximal number of binding sites. | Tritium | phospholipase A2 group IB | Rattus norvegicus |
5 | Since activation of PLA2 has been proposed to play a critical role in the formation of long-term potentiation (LTP), possibly mediated through a modification of the AMPA receptors, the results strengthen the hypothesis that PLA2-induced modification of [3H]AMPA binding sites is an important component of synaptic plasticity. | Tritium | phospholipase A2 group IB | Rattus norvegicus |
6 | Since activation of PLA2 has been proposed to play a critical role in the formation of long-term potentiation (LTP), possibly mediated through a modification of the AMPA receptors, the results strengthen the hypothesis that PLA2-induced modification of [3H]AMPA binding sites is an important component of synaptic plasticity. | Tritium | phospholipase A2 group IB | Rattus norvegicus |