Title : Adenosine downregulates DPPIV on HT-29 colon cancer cells by stimulating protein tyrosine phosphatase(s) and reducing ERK1/2 activity via a novel pathway.

Pub. Date : 2006 Sep

PMID : 16611738






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The increase in protein tyrosine phosphatase activity leads to a decrease in the tyrosine phosphorylation of ERK1/2 MAP kinase that in turn links to the decline in DPPIV mRNA and protein. Tyrosine dipeptidyl peptidase 4 Homo sapiens