Pub. Date : 1991 Nov
PMID : 1660913
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Poly I:C-induced anti-herpes simplex virus type 1 activity in inflammatory macrophages is mediated by induction of interferon-beta. | Poly I-C | interferon beta 1 | Homo sapiens |
| 2 | In addition, we demonstrate that supernatants from macrophages treated with Poly I:C contain IFN-beta but not IFN-alpha. | Poly I-C | interferon beta 1 | Homo sapiens |
| 3 | Taken together these data indicate that the antiviral effects of Poly I:C in inflammatory macrophages are mediated solely by IFN-beta, which acts in an autocrine manner to induce resistance to HSV-1. | Poly I-C | interferon beta 1 | Homo sapiens |