Pub. Date : 1991 Sep 24
PMID : 1660816
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | injection of tianeptine (10 mg/kg), 120 min before stress caused a significant decrease of ACTH and corticosterone levels. | tianeptine | proopiomelanocortin | Homo sapiens |
2 | The inhibitory effect of tianeptine on stress-induced elevations of plasma ACTH and corticosterone occurred from 1 to 3 h after the injection. | tianeptine | proopiomelanocortin | Homo sapiens |
3 | Administration of increasing doses of tianeptine revealed that only the highest doses (10 and 20 mg/kg) had a significant effect on stress-evoked stimulation of ACTH and corticosterone secretion. | tianeptine | proopiomelanocortin | Homo sapiens |