Title : Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6.

Pub. Date : 2006 May

PMID : 16606687






5 Functional Relationships(s)
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1 Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6. Bicarbonates solute carrier family 26 member 3 Homo sapiens
2 The membrane potential modulated the apparent affinity for extracellular Cl- of Cl-/HCO3- exchange by slc26a3. Bicarbonates solute carrier family 26 member 3 Homo sapiens
3 An apparent uncoupled current was also developed during the incubation of slc26a3-expressing oocytes in HCO3--buffered Cl--free media. Bicarbonates solute carrier family 26 member 3 Homo sapiens
4 These findings were used to develop a turnover cycle for Cl- and HCO3- transport by slc26a3. Bicarbonates solute carrier family 26 member 3 Homo sapiens
5 The significance of isoform-specific Cl- and HCO3- transport stoichiometry by slc26a3 and slc26a6 is discussed in the context of diseases of epithelial Cl- absorption and HCO3- secretion. Bicarbonates solute carrier family 26 member 3 Homo sapiens