Title : Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity.

Pub. Date : 2006 Jun 16

PMID : 16606610






1 Functional Relationships(s)
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1 Upon EE2 treatment, estrogen receptor alpha (ERalpha) repressed the expression of bile acid and cholesterol transporters (bile salt export pump (BSEP), Na(+)/taurocholate cotransporting polypeptide (NTCP), OATP1, OATP2, ABCG5, and ABCG8) in the liver. Bile Acids and Salts ATP binding cassette subfamily G member 5 Mus musculus