Title : Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.

Pub. Date : 2006 May

PMID : 16606369






1 Functional Relationships(s)
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1 The tangles of Alzheimer"s disease (AD) are comprised of the tau protein displaying numerous alterations, including phosphorylation at serine 422 (S422) and truncation at aspartic acid 421 (D421). Aspartic Acid microtubule associated protein tau Homo sapiens