Title : In vitro inhibition by defibrotide of monocyte superoxide anion generation: a possible mechanism for the antithrombotic effect of a polydeoxyribonucleotide-derived drug.

Pub. Date : 1991

PMID : 1660014






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In contrast, at concentrations that may be achieved in vivo following the administration of the drug (5-20 micrograms/ml), D impaired in a dose-dependent manner (p less than 0.05) the generation of O-2 in response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP, 1 microM) or calcium ionophore A23187 (10 microM). Calcium immunoglobulin kappa variable 1D-39 Homo sapiens