Title : Phosphorylation regulates Myc expression via prolonged activation of the mitogen-activated protein kinase pathway.

Pub. Date : 2006 Jul

PMID : 16596619






2 Functional Relationships(s)
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1 Furthermore, Cpd 5 inhibited c-Myc transcriptional activity and DNA binding ability, and this inhibition was antagonized by ERK kinase (MEK) inhibitor U-0126, implying that the ERK pathway was involved in regulating c-Myc expression. U 0126 MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 Furthermore, Cpd 5 inhibited c-Myc transcriptional activity and DNA binding ability, and this inhibition was antagonized by ERK kinase (MEK) inhibitor U-0126, implying that the ERK pathway was involved in regulating c-Myc expression. U 0126 MYC proto-oncogene, bHLH transcription factor Homo sapiens