Title : Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation.

Pub. Date : 2006 May

PMID : 16596182






2 Functional Relationships(s)
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1 Our results suggest that the ability of CDDP to kill these cells can be mediated by JNK, p38 MAPK and ROS, but not by ERK. Cisplatin mitogen-activated protein kinase 8 Homo sapiens
2 Therefore, the JNK pathway appears to be an ideal target for the modulation of the lethal action of CDDP in multiple types of p53-mutated cells. Cisplatin mitogen-activated protein kinase 8 Homo sapiens