Title : The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

Pub. Date : 2006 Jun

PMID : 16595597






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 After 24-h exposure to high (16.7 mmol/liter) glucose concentration, impairment of glibenclamide-induced insulin release was significantly (P = 0.01) worse with the E23K variant. Glyburide insulin Homo sapiens