Pub. Date : 1991
PMID : 1657739
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effects of the phagocyte-derived reactive oxidants hydrogen peroxide (H2O2) and hypochlorous acid (HOC1) on the activity of poly(ADP-ribose) polymerase (pADP RP), an enzyme involved in DNA repair, and on the induction and repair of DNA strand breaks in human mononuclear leukocytes (MNL) have been investigated in vitro. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 2 | The effects of the phagocyte-derived reactive oxidants hydrogen peroxide (H2O2) and hypochlorous acid (HOC1) on the activity of poly(ADP-ribose) polymerase (pADP RP), an enzyme involved in DNA repair, and on the induction and repair of DNA strand breaks in human mononuclear leukocytes (MNL) have been investigated in vitro. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 3 | The effects of the phagocyte-derived reactive oxidants hydrogen peroxide (H2O2) and hypochlorous acid (HOC1) on the activity of poly(ADP-ribose) polymerase (pADP RP), an enzyme involved in DNA repair, and on the induction and repair of DNA strand breaks in human mononuclear leukocytes (MNL) have been investigated in vitro. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 4 | The effects of the phagocyte-derived reactive oxidants hydrogen peroxide (H2O2) and hypochlorous acid (HOC1) on the activity of poly(ADP-ribose) polymerase (pADP RP), an enzyme involved in DNA repair, and on the induction and repair of DNA strand breaks in human mononuclear leukocytes (MNL) have been investigated in vitro. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 5 | Exposure of MNL to reagent H2O2 was accompanied by DNA damage and activation of pADP RP. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |
| 6 | Furthermore, HOCl caused a dose-related decrease in the activity of pADP RP in both control and H2O2-exposed MNL. | Hydrogen Peroxide | poly(ADP-ribose) polymerase 1 | Homo sapiens |